Because skin can never be completely sterilized, bacteria that rebound and multiply—even after meticulous prepping and draping—are a leading cause of SSI's. That's why you need INTEGUSEAL* Microbial Sealant: it's been shown to seal and immobilize skin flora that preps miss—including MRSA, S. epidermidis, and E. coli—keeping them from migrating into the surgical incision.